Dallas Keuchel, the reigning American League Cy Young Award winner, will look to follow up his strong Opening Day performance when he takes the mound for Sunday's series finale against the Brewers. The two clubs split the first two games.
After allowing two early runs against the Yankees on Tuesday, Keuchel retired the final 11 batters he faced to earn his first win of the season.
Keuchel is 0-2 with an 11.68 ERA in three career starts against Milwaukee. All three of those starts came during Keuchel's rookie season of 2012, Houston's last year in the National League. Only Ryan Braun, Jonathan Lucroy and Martin Maldonado remain on Milwaukee's roster from the last time Keuchel faced the Brewers.
Milwaukee will counter with Jimmy Nelson, who took a loss Tuesday against the Giants despite allowing just two runs over 7 1/3 innings.
Three things to know about this game
• Astros rookie first baseman Tyler White drove in a pair of runs during Saturday's 6-4 win to set a franchise record with nine RBIs in his first five career games. George Bjorkman (1983) and Orlando Miller (1994) previously held the record at seven.
• Houston has homered in its first five games this season, matching a franchise record set in 1988. Five players have hit home runs for the Astros, with shortstop Carlos Correa and White leading the way with three.
• After homering just six times in 391 plate appearances last season, Brewers second baseman Scooter Gennett has three home runs in his first five games of 2016.