Chandler Whitmer threw for 209 yards and two touchdowns as the Huskies fell to Boise State 38-21 on Saturday.
Deshon Foxx lead all receivers with 107 yards, averaging nearly 18 yards a catch.
Boise State quarterback Grant Hedrick threw two touchdowns to Matt Miller and caught one from the senior receiver on a trick play.
A 9-yard strike from Hedrick to Miller in the back of the end zone gave the Broncos a 31-21 lead in the fourth quarter after UConn had closed the gap to three points.
Connecticut held Boise State running back Jay Ajayi, who came in averaging 158 yards a game and nearly 6 yards a run, to just 39 yards on 18 carries.
The Huskies look to rebound next Friday at USF.